Doubly robust estimation of attributable fractions

Attributable fractions

Attributable fraction (AF) is an important concept in clinical and epidemiological studies. The concept has mainly been discussed in relation to case–control studies, cross-sectional studies, and follow-up studies of fixed length. Here, we propose and discuss several ways of defining and estimating AFs with right-censored survival data, and thus with varying lengths of follow-up. In particular,...

Three Essays on Doubly Robust Estimation Methods

Practice of Epidemiology Doubly Robust Estimation of Causal Effects

Doubly robust estimation combines a form of outcome regression with a model for the exposure (i.e., the propensity score) to estimate the causal effect of an exposure on an outcome. When used individually to estimate a causal effect, both outcome regression and propensity score methods are unbiased only if the statistical model is correctly specified. The doubly robust estimator combines these ...

Doubly robust estimation of the local average treatment effect curve.

We consider estimation of the causal effect of a binary treatment on an outcome, conditionally on covariates, from observational studies or natural experiments in which there is a binary instrument for treatment. We describe a doubly robust, locally efficient estimator of the parameters indexing a model for the local average treatment effect conditionally on covariates V when randomization of t...

Doubly Robust Estimation of Optimal Dynamic Treatment Regimes

We compare methods for estimating optimal dynamic decision rules from observational data, with particular focus on estimating the regret functions defined by Murphy (in J. R. Stat. Soc., Ser. B, Stat. Methodol. 65:331-355, 2003). We formulate a doubly robust version of the regret-regression approach of Almirall et al. (in Biometrics 66:131-139, 2010) and Henderson et al. (in Biometrics 66:1192-...